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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 131732Generated: October 31, 2026

Methyl iodide → 2'-Methyl-N-methyl-N-(2-methylbenzyl)-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1'-biphenyl-4-carboxamide

https://huagongshe.com/reaction/131732

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant2'-Methyl-N-(2-methylbenzyl)-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1'-biphenyl-4-carboxamideHCID 10222443—
Product2'-Methyl-N-methyl-N-(2-methylbenzyl)-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1'-biphenyl-4-carboxamideHCID 10295101—

Reaction Steps

2′-Methyl-N-methyl-N-(2-methylbenzyl)-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide was prepared from 2′-methyl-N-(2-methylbenzyl)-5′-(5-methyl-1,3,4-oxadiazol-2-yl)-1,1′-biphenyl-4-carboxamide and iodomethane using method L. NMR; δH [2H6]—DMSO 7.89,(1H, m), 7.77,(1H, m), 7.59-7.43,(5H, m), 7.22,(4H, m), 4.71-4.53,(2H, m), 2.93-2.87,(3H, m), 2.55,(3H, s), 2.32-2.29,(3H, m). LCMS; retention time 3.48 min, MH+ 412.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07384963B2
Source datasetuspto-grants-2008_06
ORD IDord-ae2074fb0b4849c7bfcab9c20b44358f
Source noteuspto-grants-2008_06