HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13191Generated: October 25, 2026
2-(carbamoylamino)-N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acetamide → HCID 44595798, compound
https://huagongshe.com/reaction/13191
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-(carbamoylamino)-N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acetamide | HCID 59339658 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 44595798 | HCID 44595798 | — |
Reaction Steps
2-(carbamoylamino)-N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acetamide (270, 141 mg, 0.29 mmol) was dissolved in acetic acid (3 mL). The reaction was heated at 120° C. with stirring for 20 h. The HOAc was evaporated and the product was purified by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07728030B2 |
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| Source dataset | uspto-grants-2010_06 |
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| ORD ID | ord-736b3f03b3274a69b94fabb49b195670 |
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| Source note | uspto-grants-2010_06 |
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