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HRID132804

反应详情

EQUATION

反应方程式

HRID 132804 的结构方程式

REACTANTS

反应物

3
结构：CCN(CC)CC
HCID8471

Triethylamine

C6H15N

结构：CS(=O)(=O)Cl
HCID31297

Methanesulfonyl chloride

CH3ClO2S

结构：CC(C)(C)OC(=O)NC[C@H](O)[C@H]1COC(C)(C)O1
HCID14249481

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)NC[C@H](OS(C)(=O)=O)[C@H]1COC(C)(C)O1
HCID86591233

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Alcohol 24 was dissolved in dichloromethane and cooled to 0°. Triethylamine and methanesulfonyl chloride were added and the solution stirred until the reaction was completed. The solution was extracted and the solvent removed to obtain the mesylate (25) which was purified using silica gel column chromatography. Solvent removal afforded a liquid.

WORKUP

后处理

  1. temperaturecooled to 0°
  2. extractionThe solution was extracted
  3. customthe solvent removed