反应详情

A solution of the product (94 mg, 0.20 mmol) from Step A above in 0.5 mL of methanol and 2.0 mL of 4.0M hydrogen chloride in 1,4-dioxane was kept at room temperature for 18 h. The reaction mixture was concentrated under a stream of nitrogen, and the residue was triturated with ether. The resultant precipitate was collected and dried in vacuo to afford the title compound as a pale yellow powder. LC/MS 203.1 (M+1).

1. concentrationThe reaction mixture was concentrated under a stream of nitrogen
2. customthe residue was triturated with ether
3. customThe resultant precipitate was collected
4. customdried in vacuo