HCID 17979855, compound → HCID 17979842, compound

Participants

Reaction Steps

0.24 g of palladium on charcoal (10% Pd) is added to a solution of 1.32 g of 2-amino-3-nitro-6-methylquinoline (compound B2) in 100 ml of methanoltetrahydrofurane 1:1. After hydration for 1.5 h, the catalyst is filtered off and the filtrate is concentrated in vacuo. The residue is chomatographed on silica gel (dichloromethane/methanol 8:1). 1.02 g of the title compound are obtained as colourless solid.

Provenance & Evidence