Ammonia → HCID 17979844, compound

HRID 133095Notes

Reaction equation

HRID 133095 reaction equation
Cl[C:2]1[C:11]([N+:12]([O-:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Br:15])[CH:8]=2)[N:3]=1.[NH3:16]>>[NH2:16][C:2]1[C:11]([N+:12]([O-:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Br:15])[CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 179798546-bromo-2-chloro-3-nitroquinoline2×

Product 1

HCID 17979844HCID 17979844, compound

Conditions

Temperature
120 °C

Procedure

0.8 g of 2-chloro-6-bromo-3-nitroquinoline (compound C4) are dissolved in 12 ml of ethanolic ammonia solution and stirred at 120° C. for 2.5 h in an autoclave. Under cooling in an ice bath, 0.55 g of the title compound precipitate from the reaction mixture as red crystals.

Workup

  1. temperatureUnder cooling in an ice bath

Sources & evidence

ORD record
ord-050668d0f5b345d4bf85526da67674ba
Source dataset
uspto-grants-2008_06
Patent number
US07390819B2

Reaction notes

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