反应详情

温度

0 °C

5 g of 1-(4-methylphenyl)hydrazine hydrochloride are dissolved in water and then triethylamine is added until the salt has been neutralized. Extraction is carried out with AcOEt and then the extract is evaporated to dryness. The precipitate formed is dissolved in 30 ml of ether and then a solution of 4.6 ml of acetic anhydride dissolved in 30 ml of ether is added dropwise. The mixture is stirred at 0° C. for 15 minutes and then the precipitate formed is filtered off to produce 3 g of the expected compound.

1. extractionExtraction
2. customthe extract is evaporated to dryness
3. customThe precipitate formed
4. additionis added dropwise
5. customthe precipitate formed
6. filtrationis filtered off