反应详情

5 g of 3-bromophenylacetic acid are dissolved in 80 ml of ethanol, 3 ml of concentrated H2SO4 are added and then the mixture is heated at reflux for two hours. The ethanol is evaporated, neutralization is carried out with a saturated K2CO3 solution and then extraction is carried out with AcOEt. The organic phase is dried over MgSO4. 5.2 g of the expected compound are obtained in the liquid form.

1. temperaturethe mixture is heated
2. temperatureat reflux for two hours
3. customThe ethanol is evaporated
4. extractionextraction
5. dry with materialThe organic phase is dried over MgSO4