反应详情

To a solution of 3.4 g of 1-(4-chlorophenyl)-2-methyl-2-trimethylsilyloxy-propan-1-one in 10 mL of methanol 4 mL of 2N HCl was added and the mixture was stirred for 3 hr. The reaction was diluted with CH2Cl2 and washed with water, brine, dried and concentrated to give the title compound which was used in the next step without purification. 1H NMR: (500 MHz, CDCl3): δ 1.65 (s, 6H), 7.47 (d, 2H), 8.03 (d, 2H)

1. washwashed with water, brine
2. customdried
3. concentrationconcentrated