Methacryloyl chloride → N-(4-Cyano-3-methylphenyl)-2-methylprop-2-enamide

HRID 133743Notes

Reaction equation

[NH2:1][C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([CH3:10])[CH:3]=1.[C:11](Cl)(=[O:15])[C:12]([CH3:14])=[CH2:13]>>[C:6]([C:5]1[CH:8]=[CH:9][C:2]([NH:1][C:11](=[O:15])[C:12]([CH3:14])=[CH2:13])=[CH:3][C:4]=1[CH3:10])#[N:7]

Participants

Reactant 2

HCID 13528Methacryloyl chloride

HCID 81670814-Amino-2-methylbenzonitrile

Product 1

HCID 59645512N-(4-Cyano-3-methylphenyl)-2-methylprop-2-enamide

Procedure

N-(4-Cyano-3-methylphenyl)-2-methylacrylamide was prepared as described in Example 1 starting from 4-amino-2-methylbenzonitrile and methacryloyl chloride.

Sources & evidence

ORD record: ord-ae974a8b6c0c484e9331176cd337c86d
Source dataset: uspto-grants-2008_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07390923B2

Reaction notes

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