HRID13391

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID78288

Glycine, N-[(1,1-dimethylethoxy)carbonyl]-

C7H13NO4

结构：CS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2C2CCCN2)cc1

HCID23145175

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)NCC(=O)N1CCCC1c1cc2[nH]c(-c3ccccn3)nc2cc1Oc1ccc(S(C)(=O)=O)cc1

HCID86619214

未命名化合物

PROCEDURE

实验过程

The entitled compound was obtained in the same method as in Example 171 and 181 or in accordance with the method or by combining it with an ordinary method but using 5-(4-methanesulfonyl-phenoxy)-2-pyridin-2-yl-6-pyrrolidin-2-yl-1H-benzimidazole obtained in Example 162 (step 7) and N-t-butoxycarbonyl-glycine.

WORKUP

后处理

customThe entitled compound was obtained in the same method as in Example 171 and 181 or in accordance with the method

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-14c0c2104d9d4b868d1102d3db6bba65
来源数据集: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07728025B2
来源说明: uspto-grants-2010_06

反应 SMILES

[CH3:1][S:2]([C:5]1[CH:31]=[CH:30][C:8]([O:9][C:10]2[C:24]([CH:25]3[CH2:29][CH2:28][CH2:27][NH:26]3)=[CH:23][C:13]3[NH:14][C:15]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=4)=[N:16][C:12]=3[CH:11]=2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[C:32]([O:36][C:37]([NH:39][CH2:40][C:41](O)=[O:42])=[O:38])(C)(C)[CH3:33]>>[CH3:1][S:2]([C:5]1[CH:6]=[CH:7][C:8]([O:9][C:10]2[C:24]([CH:25]3[CH2:29][CH2:28][CH2:27][N:26]3[C:41](=[O:42])[CH2:40][NH:39][C:37](=[O:38])[O:36][CH2:32][CH3:33])=[CH:23][C:13]3[NH:14][C:15]([C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=4)=[N:16][C:12]=3[CH:11]=2)=[CH:30][CH:31]=1)(=[O:3])=[O:4]