Hydrochloric Acid → Ethyl 6-(6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-yl)-1-((1-(2-morpholinoethyl)pyrrolidin-3-yl)methyl)-4-oxo-1,4-dihydroquinoline-3-carboxylate
Reaction equation
[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:34]2[s:35][cH:36][c:37]([C:39]([F:40])([F:41])[F:42])[n:38]2)[c:9](-[c:12]2[cH:13][c:14]3[c:15](=[O:33])[c:16]([C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:17][n:18]([CH2:22][CH:23]4[CH2:24][NH:25][CH2:26][CH2:27]4)[c:19]3[cH:20][cH:21]2)[cH:10][n:11]1)=[O:43].[CH3:55][OH:56].[ClH:44].[O:46]1[CH2:47][CH2:48][N:49]([CH2:52][CH:53]=[O:54])[CH2:50][CH2:51]1.[OH2:45]>>[CH2:1]([CH3:2])[NH:3][C:4]([NH:5][c:6]1[cH:7][c:8](-[c:34]2[s:35][cH:36][c:37]([C:39]([F:40])([F:41])[F:42])[n:38]2)[c:9](-[c:12]2[cH:13][c:14]3[c:15](=[O:33])[c:16]([C:28](=[O:29])[O:30][CH2:31][CH3:32])[cH:17][n:18]([CH2:22][CH:23]4[CH2:24][N:25]([CH2:53][CH2:52][N:49]5[CH2:48][CH2:47][O:46][CH2:51][CH2:50]5)[CH2:26][CH2:27]4)[c:19]3[cH:20][cH:21]2)[cH:10][n:11]1)=[O:43]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ca9f0cee132741e49cfe2b0c1dd0dae6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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