Ethyl Acetate → 3-[3-chloro-4-(2-methyl-2H-[1,2,4]triazol-3-yl)-thiophen-2-yl]-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine

HRID 133975Notes

Reaction equation

HRID 133975 reaction equation
[Br:1][c:2]1[c:3]([Cl:23])[c:4](-[c:7]2[c:8]([CH3:22])[n:9][c:10]3[n:11]2[n:12][c:13]([CH3:21])[cH:14][c:15]3[CH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[s:5][cH:6]1.[Br:24][c:25]1[n:26][cH:27][n:28][n:29]1[CH3:30].[CH3:31][CH2:32][O:33][C:34]([CH3:35])=[O:36]>>[c:2]1(-[c:25]2[n:26][cH:27][n:28][n:29]2[CH3:30])[c:3]([Cl:23])[c:4](-[c:7]2[c:8]([CH3:22])[n:9][c:10]3[n:11]2[n:12][c:13]([CH3:21])[cH:14][c:15]3[CH:16]([CH2:17][CH3:18])[CH2:19][CH3:20])[s:5][cH:6]1

Participants

4

Reactant 3

HCID 8857Ethyl AcetateHCID 1401211H-1,2,4-Triazole, 5-bromo-1-methyl-HCID 579330783-(4-Bromo-3-chloro-thiophen-2-yl)-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine

Product 1

HCID 579330213-[3-chloro-4-(2-methyl-2H-[1,2,4]triazol-3-yl)-thiophen-2-yl]-8-(1-ethyl-propyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine

Sources & evidence

ORD record
ord-cb06e87b35944109a47601b3c9516e70
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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