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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 134003Generated: October 26, 2026

Dichloromethane → 5-(3,3-dimethyl-but-1-ynyl)-3-(N-tert-butoxycarbonyl-piperidin-4-yl)amino-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/134003

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantDibutyltin dichlorideHCID 12688—
ReactantPhenylsilaneHCID 12752—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantMethyl 3-amino-5-(3,3-dimethylbut-1-yn-1-yl)thiophene-2-carboxylateHCID 24989346—
Product5-(3,3-dimethyl-but-1-ynyl)-3-(N-tert-butoxycarbonyl-piperidin-4-yl)amino-thiophene-2-carboxylic acid methyl esterHCID 66603530—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-2d860f1b02c54a4687e312dc96ce1d4e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)