反应详情

The mixture containing 2-bromo-5-methoxybenzthiazole (1 eq), 4-Bromoaniline (2 eq) and disopropylethylamine was subjected to microwave in NMP at 220° C. The resultant mixture was concentrated and partitioned between ethyl acetate and water. The organic layer was washed with brine and dried. Purification on silica gel gave the desired product. MS: MH+=335

1. concentrationThe resultant mixture was concentrated
2. custompartitioned between ethyl acetate and water
3. washThe organic layer was washed with brine
4. customdried
5. customPurification on silica gel