Hydrogen Bromide → 6-[2-[4-[(2,4-difluorophenyl)(hydroxyimino)methyl]-1-piperazinyl]ethyl]-2,3-dihydro-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one
Reaction equation
[Br:2][CH2:3][CH2:4][c:5]1[c:6]([CH3:15])[n:7][c:8]2[n:9]([c:10]1=[O:11])[CH2:12][CH2:13][S:14]2.[BrH:1].[C:33](=[O:34])([O-:35])[OH:36].[CH3:38][CH:39]([CH3:40])[CH2:41][C:42](=[O:43])[CH3:44].[F:16][c:17]1[c:18]([C:24]([N:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]2)=[N:31][OH:32])[cH:19][cH:20][c:21]([F:23])[cH:22]1.[Na+:37]>>[CH2:3]([CH2:4][c:5]1[c:6]([CH3:15])[n:7][c:8]2[n:9]([c:10]1=[O:11])[CH2:12][CH2:13][S:14]2)[N:28]1[CH2:27][CH2:26][N:25]([C:24]([c:18]2[c:17]([F:16])[cH:22][c:21]([F:23])[cH:20][cH:19]2)=[N:31][OH:32])[CH2:30][CH2:29]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5b6fa2309fb84a269fe43ed29b0ce2b0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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