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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 134637Generated: October 30, 2026

Dimethylformamide → 2-tert-Butyl-4-chloro-6-(trifluoromethyl)pyrimidine

https://huagongshe.com/reaction/134637

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantThionyl ChlorideHCID 24386—
ReactantHCID 178441869HCID 178441869—
Product2-tert-Butyl-4-chloro-6-(trifluoromethyl)pyrimidineHCID 15837483—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-3b2325bdf75f473ebc2286b3bf385663
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)