Dimethylformamide → 2-tert-Butyl-4-chloro-6-(trifluoromethyl)pyrimidine
Reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[c:14]1[n:15][c:16]([C:21]([F:22])([F:23])[F:24])[cH:17][c:18]([OH:20])[n:19]1.[Cl:25][CH2:26][Cl:27].[O:5]=[CH:6][N:7]([CH3:8])[CH3:9].[S:1]([Cl:2])([Cl:3])=[O:4]>>[Cl:3][c:18]1[cH:17][c:16]([C:21]([F:22])([F:23])[F:24])[n:15][c:14]([C:10]([CH3:11])([CH3:12])[CH3:13])[n:19]1Participants
5
Sources & evidence
- ORD record
- ord-3b2325bdf75f473ebc2286b3bf385663
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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