N-methyl-2-pyrrolidone → 2-(3-Acetamido-4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)-4-(3-fluorobenzylamino)pyrimidine-5-carboxamide
Reaction equation
[CH3:48][N:49]1[CH2:50][CH2:51][CH2:52][C:53]1=[O:54].[NH2:29][c:30]1[cH:31][cH:32][c:33]([O:40][CH2:41][CH2:42][N:43]2[CH2:44][CH2:45][CH2:46][CH2:47]2)[c:34]([NH:36][C:37]([CH3:38])=[O:39])[cH:35]1.[n:1]1([O:2][c:11]2[n:12][cH:13][c:14]([C:26](=[O:27])[NH2:28])[c:15]([NH:17][CH2:18][c:19]3[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]3)[n:16]2)[c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[n:9][n:10]1>>[c:11]1([NH:29][c:30]2[cH:31][cH:32][c:33]([O:40][CH2:41][CH2:42][N:43]3[CH2:44][CH2:45][CH2:46][CH2:47]3)[c:34]([NH:36][C:37]([CH3:38])=[O:39])[cH:35]2)[n:12][cH:13][c:14]([C:26](=[O:27])[NH2:28])[c:15]([NH:17][CH2:18][c:19]2[cH:20][c:21]([F:25])[cH:22][cH:23][cH:24]2)[n:16]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-fa65363decb545e3af92c0dff027e119
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…