Hydrochloric Acid → HCID 23111557, compound

HRID 1348502Notes

Reaction equation

HRID 1348502 reaction equation
[OH-].[Na+].[CH3:3][O:4][C:5]1[C:10]([CH3:11])=[CH:9][C:8]([NH:12][C:13](=[O:18])[O:14][CH2:15][CH2:16]Cl)=[CH:7][C:6]=1[NH:19][C:20](=[O:25])[O:21][CH2:22][CH2:23]Cl.Cl>O1CCOCC1>[CH3:3][O:4][C:5]1[C:10]([CH3:11])=[CH:9][C:8]([N:12]2[CH2:16][CH2:15][O:14][C:13]2=[O:18])=[CH:7][C:6]=1[N:19]1[CH2:23][CH2:22][O:21][C:20]1=[O:25]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 86602379HCID 86602379, compound

Product 1

HCID 23111557HCID 23111557, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Conditions

Temperature
45 °C

Procedure

200 ml of sodium hydroxide solution (20% strength) were initially introduced and heated to 45° C. Subsequently, 59 g of bis(2-chloroethyl) (4-methoxy-5-methyl-1,3-phenylene)biscarbamate were added in portions and the mixture was diluted with 200 ml of dioxane. The mixture was after-stirred for a further 2 h at 45° C. After stirring overnight at room temperature, the mixture was poured onto ice, and the mixture was neutralized with hydrochloric acid. The precipitated product was filtered off with suction and dried overnight under reduced pressure.

Workup

  1. stirringAfter stirring overnight at room temperature
  2. additionthe mixture was poured onto ice
  3. filtrationThe precipitated product was filtered off with suction
  4. customdried overnight under reduced pressure

Sources & evidence

ORD record
ord-0a6bb4abb0ea46b188b38626ba29424e
Source dataset
uspto-grants-2007_05
Patent number
US07211119B2

Reaction notes

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