Piperidine → HCID 73446800, compound

HRID 1348523Notes

Reaction equation

HRID 1348523 reaction equation
[CH3:1][C:2]1[O:3][C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:5][C:6](=[C:8]([C:11]#[N:12])[C:9]#[N:10])[CH:7]=1.[C:19]1([CH:25]2[N:29]([C:30]3[CH:37]=[CH:36][C:33]([CH:34]=O)=[CH:32][CH:31]=3)[N:28]=[C:27]([C:38]3[C:51]4[C:52]5=[C:53]6[C:48](=[CH:49][CH:50]=4)[CH:47]=[CH:46][CH:45]=[C:44]6[CH:43]=[CH:42][C:41]5=[CH:40][CH:39]=3)[CH2:26]2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.N1CCCCC1>C(O)C>[C:13]1([C:4]2[O:3][C:2]([CH:1]=[CH:34][C:33]3[CH:36]=[CH:37][C:30]([N:29]4[CH:25]([C:19]5[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=5)[CH2:26][C:27]([C:38]5[C:51]6[C:52]7=[C:53]8[C:48](=[CH:49][CH:50]=6)[CH:47]=[CH:46][CH:45]=[C:44]8[CH:43]=[CH:42][C:41]7=[CH:40][CH:39]=5)=[N:28]4)=[CH:31][CH:32]=3)=[CH:7][C:6](=[C:8]([C:11]#[N:12])[C:9]#[N:10])[CH:5]=2)[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

5

Reactant 3

HCID 8082PiperidineHCID 789785HCID 789785, compoundHCID 18458009HCID 18458009, compound

Product 1

HCID 73446800HCID 73446800, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
75 °C

Procedure

As shown in the following reaction 8, 0.24 g (1.0 mmol) of 2-(2-methyl-6-phenyl-pyran-4-ylidene)-malononitrile and 0.46 g (1.0 mmol) of 4-(5-phenyl-3-pyren-1-yl-4,5-dihydro-pyrazol-1-yl)benzaldehyde were added into 20 ml of ethanol, and 0.13 g (1.53 mmol) of piperidine was added thereto. The reaction solution was heated at 75° C. for 10 hours.

Workup

  1. additionwas added

Sources & evidence

ORD record
ord-d2ece438a18f4c03ad8651163df4125f
Source dataset
uspto-grants-2007_05
Patent number
US07211335B2

Reaction notes

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