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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1348711Generated: October 26, 2026

Dimethylamine → 4-dimethylaminomethyl-6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/1348711

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-oneHCID 86605972—
Product4-dimethylaminomethyl-6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-2H-pyridazin-3-oneHCID 2199147988.6%

Reaction Steps

Following the procedure of Example 7, 6-(3-fluoro-4-methoxyphenyl)-2-isobutyl-4-methanesulfonyloxymethyl-2H-pyridazin-3-one and dimethylamine were reacted to yield the title compound as a yellow oil (yield: 88.6%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07211577B2
Source datasetuspto-grants-2007_05
ORD IDord-16d86800bf524c11af02d9c6acedba3a
Source noteuspto-grants-2007_05