1-Methylpiperazine → HCID 67213294, compound

HRID 1348722Notes

Reaction equation

HRID 1348722 reaction equation
[CH2:1]([N:5]1[C:10](=[O:11])[C:9]([CH2:12]OS(C)(=O)=O)=[CH:8][C:7]([C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=2)=[N:6]1)[CH:2]([CH3:4])[CH3:3].[CH3:28][N:29]1[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]1>>[CH2:1]([N:5]1[C:10](=[O:11])[C:9]([CH2:12][N:32]2[CH2:33][CH2:34][N:29]([CH3:28])[CH2:30][CH2:31]2)=[CH:8][C:7]([C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=2)=[N:6]1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 219915502-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromet hylphenyl)-2H-pyridazin-3-one

Product 1

HCID 67213294HCID 67213294, compoundYield 81.1%

Procedure

Following the procedure of Example 1(10), 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one and 1-methylpiperazine were reacted to yield the title compound as a yellow oil (yield: 81.1%).

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-0e4faa128d3342f188bc537cef2b3d03
Source dataset
uspto-grants-2007_05
Patent number
US07211577B2

Reaction notes

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