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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1348747Generated: October 26, 2026

Propargylamine → 2-isobutyl-6-[4-(methylthio)phenyl]-4-propargylaminomethyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/1348747

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropargylamineHCID 239041—
Reactant2-isobutyl-4-methanesulfonyloxymethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-oneHCID 21991488—
Product2-isobutyl-6-[4-(methylthio)phenyl]-4-propargylaminomethyl-2H-pyridazin-3-oneHCID 992411952.2%

Reaction Steps

Following the procedure of Example 1(10), 2-isobutyl-4-methanesulfonyloxymethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one and propargylamine were reacted to yield the title compound as a yellow oil (yield: 52.2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07211577B2
Source datasetuspto-grants-2007_05
ORD IDord-2730924445334ddb9241521fc87d39f2
Source noteuspto-grants-2007_05