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HRID1348921

反应详情

EQUATION

反应方程式

HRID 1348921 的结构方程式

REACTANTS

反应物

2
结构：Cl.NNc1ccc2c(c1)OCO2
HCID22291622

(2H-1,3-Benzodioxol-5-yl)hydrazine--hydrogen chloride (1/1)

C7H9ClN2O2

结构：CCOC(=O)C(=O)C1CN(C(C)=O)c2ccc([N+](=O)[O-])cc2C1=O
HCID58859529

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1nn(-c2ccc3c(c2)OCO3)c2c1CN(C(C)=O)c1ccc([N+](=O)[O-])cc1-2
HCID21092643

未命名化合物

收率 78%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

CONDITIONS

反应条件

温度
60 °C

PROCEDURE

实验过程

The material of Step 3 (1.1 g, 0.00331 mol) and 1-(1,3-benzodioxol-5-yl)hydrazine hydrochloride (500 mg, 0.00265 mol) were combined in acetic acid (10 mL) and heated to 60° C. for 5 hours. The suspension was then cooled and filtered to give the product as a brown solid. 930 mg (MW=450.4 g/mol, 78% yield). LC/MS m/z=451.5 (m+1).

WORKUP

后处理

  1. temperatureThe suspension was then cooled
  2. filtrationfiltered