反应详情

温度

120 °C

The material of Step 5 (450 mg, 0.00094 mol) was dissolved in ethanol (10 mL) and NH3 (10 mL), and the resulting reaction mixture was heated to 120° C. and shaken for 20 hours at 600 psi. The reaction was then cooled and vented for 2 hours. The resulting solution was concentrated in vacuo to give the product as a brown glass. 340 mg (MW=391.38, 93% yield). LC/MS m/z=392.05 (m+1).

1. temperatureThe reaction was then cooled
2. waitvented for 2 hours
3. concentrationThe resulting solution was concentrated in vacuo