HuagongsheHuagongshe Chemistry Print Report · For research reference only
ethyl 5-acetyl-1-(4-fluorophenyl)-8-nitro-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline-3-carboxylate → ethyl 5-acetyl-8-amino-1-(4-fluorophenyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | ethyl 5-acetyl-1-(4-fluorophenyl)-8-nitro-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline-3-carboxylate | HCID 21092644 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | ethyl 5-acetyl-8-amino-1-(4-fluorophenyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline-3-carboxylate | HCID 21092646 | 91% |
Reaction Steps
The product was obtained as the acetic acid salt from the material from step 1 (10 g, 0.0236 mol) and by the method of Example 17. 9.8 g. (FW=454.45, 91% yield). LC/MS m/z=395 (m+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07211597B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-c47904afd3ea4bbc90762751b04b2993 |
| Source note | uspto-grants-2007_05 |