HRID1349047

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1516507

1-Boc-3-(amino)azetidine

C8H16N2O2

HCID22223512

未命名化合物

结构：CCON=C1C[C@@H](C(=O)O)N(C(=O)OC(C)(C)C)C1

HCID58714540

未命名化合物

PRODUCTS

生成物

结构：CCCCCc1ccc(C(=O)N2CC(=NOCC)C[C@H]2C(=O)NC2CN(C(=O)OC(C)(C)C)C2)c(=O)o1

HCID131726368

未命名化合物

PROCEDURE

实验过程

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(ethoxyimino)-2-pyrrolidinecarboxylic acid, 2-oxo-6-pentyl-2H-pyran-3-carbonyl chloride, and tert-butyl 3-amino-1-azetidinecarboxylate the title compound was obtained in 100% purity by LC/MS. MS(ESI+): m/z=519.6.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-20302e6526cb4faa90b26cb1d1fa0804
来源数据集: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07211601B2
来源说明: uspto-grants-2007_05

反应 SMILES

C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][CH3:16])[CH2:10][C@H:9]1[C:17]([OH:19])=O)=[O:7])(C)(C)C.[O:20]=[C:21]1[C:26](C(Cl)=O)=[CH:25][CH:24]=[C:23]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[O:22]1.[NH2:35][CH:36]1[CH2:39][N:38]([C:40]([O:42][C:43]([CH3:46])([CH3:45])[CH3:44])=[O:41])[CH2:37]1>>[CH2:15]([O:14][N:13]=[C:11]1[CH2:12][N:8]([C:6]([C:26]2[C:21](=[O:20])[O:22][C:23]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:24][CH:25]=2)=[O:7])[C@H:9]([C:17]([NH:35][CH:36]2[CH2:37][N:38]([C:40]([O:42][C:43]([CH3:46])([CH3:45])[CH3:44])=[O:41])[CH2:39]2)=[O:19])[CH2:10]1)[CH3:16]