Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tert-butyl 3-aminoazetidine-1-carboxylate → tert-butyl 3-[([{2S,4EZ)-4-(ethoxyimino)-1-[(2-oxo-6-pentyl-2H-pyran-3-yl)carbonyl]pyrrolidinyl}carbonyl)amino]-1-azetidinecarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tert-butyl 3-aminoazetidine-1-carboxylate | HCID 1516507 | — |
| 반응물 | 2-oxo-6-pentyl-2H-pyran-3-carbonyl chloride | HCID 22223512 | — |
| 반응물 | (2S,4EZ)-1-(tertbutoxycarbonyl)-4-(ethoxyirnino)-2-pyrrolidinecarboxylic acid | HCID 58714540 | — |
| 생성물 | tert-butyl 3-[([{2S,4EZ)-4-(ethoxyimino)-1-[(2-oxo-6-pentyl-2H-pyran-3-yl)carbonyl]pyrrolidinyl}carbonyl)amino]-1-azetidinecarboxylate | HCID 131726368 | — |
반응 단계
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(ethoxyimino)-2-pyrrolidinecarboxylic acid, 2-oxo-6-pentyl-2H-pyran-3-carbonyl chloride, and tert-butyl 3-amino-1-azetidinecarboxylate the title compound was obtained in 100% purity by LC/MS. MS(ESI+): m/z=519.6.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07211601B2 |
| 출처 데이터셋 | uspto-grants-2007_05 |
| ORD ID | ord-20302e6526cb4faa90b26cb1d1fa0804 |
| 출처 메모 | uspto-grants-2007_05 |