2-Methoxyethylamine → HCID 131725498, compound

HRID 1349142Notes

Reaction equation

C(OC([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)[CH2:10][C@H:9]1[C:24]([OH:26])=O)=O)(C)(C)C.[CH3:27][O:28][CH2:29][CH2:30][NH2:31]>>[CH3:23][O:22][C:19]1[CH:18]=[CH:17][C:16]([CH2:15][O:14][N:13]=[C:11]2[CH2:12][NH:8][C@H:9]([C:24]([NH:31][CH2:30][CH2:29][O:28][CH3:27])=[O:26])[CH2:10]2)=[CH:21][CH:20]=1

Participants

Reactant 2

HCID 80182-Methoxyethylamine

HCID 58714542HCID 58714542, compound

Product 1

HCID 131725498HCID 131725498, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(4-methoxybenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid, and 2-methoxyethylamine the title compound was obtained in 52% purity by LC/MS. MS(ESI+): m/z=322.2.

Sources & evidence

ORD record: ord-955e6eeafb53424c9352a3f5276f73ef
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07211601B2

Reaction notes

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