Allylamine → HCID 131725569, compound

HRID 1349227Notes

Reaction equation

C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([OH:18])=O)=[O:7])(C)(C)C.[C:19](Cl)(=O)[CH:20]=C.[CH2:24]([NH2:27])[CH:25]=[CH2:26]>>[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([NH:27][CH2:24][CH:25]=[CH2:26])=[O:18])(=[O:7])[CH:19]=[CH2:20]

Participants

Reactant 3

HCID 7853Allylamine

HCID 13140Acryloyl chloride

HCID 58714586(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725569HCID 131725569, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, acryloyl chloride, and allylamine the title compound was obtained in 81% purity by LC/MS. MS(ESI+): m/z=252.0.

Sources & evidence

ORD record: ord-f6fecb922ca547ff8ab31db4035963ba
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07211601B2

Reaction notes

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