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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1349334Generated: October 31, 2026

1-(4-(Trifluoromethyl)phenyl)piperazine → HCID 131725664, compound

https://huagongshe.com/reaction/1349334

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-(Trifluoromethyl)phenyl)piperazineHCID 121718—
Reactant2'-Methyl-biphenyl-4-carboxylic acidHCID 2759815—
Reactant(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acidHCID 58714586—
ProductHCID 131725664HCID 131725664—

Reaction Steps

Following the general method as outlined in Example 22, staring from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 2′-methyl[1,1′-biphenyl]-4-carboxylic acid, and 1-[4-(trifluoromethyl)phenyl]piperazine, the title compound was obtained in 89% purity by HPLC. MS(ESI+): m/z=565.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07211601B2
Source datasetuspto-grants-2007_05
ORD IDord-3c2b18bb8bd04566b995068d1cda3fc4
Source noteuspto-grants-2007_05