HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10272812, compound → HCID 69113779, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10272812 | HCID 10272812 | — |
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 69113779 | HCID 69113779 | — |
Reaction Steps
(2R)-1-[1,1-Dimethyl-2-(naphthalen-2-yl)ethylamino]-3-[1-(2-methoxyphenyl)ethoxy]propan-2-ol (141 mg) obtained in Example 4 was dissolved in diethyl ether (5 ml), and 4N hydrogen chloride-ethyl acetate solution was added. The reaction mixture was concentrated under reduced pressure and diethyl ether (5 ml) was added. The mixture was concentrated under reduced pressure to give the title compound (154 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07211685B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-78c4df7c1de14d2c991649e8a6b72a5a |
| Source note | uspto-grants-2007_05 |