HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(2-Bromoethoxy)-7-fluoro-2-methylquinoline → 8-{1-[2-(7-Fluoro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4-methyl-4H-benzo[1,4]oxazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(2-Bromoethoxy)-7-fluoro-2-methylquinoline | HCID 17965142 | — |
| Reactant | 4-methyl-8-(piperidin-4-ylmethyl)4H-benzo[1,4]oxazin-3-one | HCID 21093745 | — |
| Product | 8-{1-[2-(7-Fluoro-2-methylquinolin-5-yloxy)ethyl]piperidin-4-ylmethyl}-4-methyl-4H-benzo[1,4]oxazin-3-one | HCID 10217200 | — |
Reaction Steps
The title compound was prepared from 4-methyl-8-(piperidin-4-ylmethyl)-4H-benzo[1,4]oxazin-3-one and 5-(2-bromoethoxy)-7-fluoro-2-methylquinoline in a similar manner to Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07214674B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-41357284c1584299bcda5ab6dbdaee04 |
| Source note | uspto-grants-2007_05 |