反应详情

To a solution of 3.0 g (11.7 mmol) of 7,7-dimethyl-2-(pyridin-4-yl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one in 75 ml of acetic acid was added dropwise 0.6 ml (11.7 mmol) of bromine. The mixture was allowed to stir at room temperature for 2 h.