HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 3-Bromo-7,7-dimethyl-2-(pyridin-4-yl)-6,7,8,9-tetrahydro-4h-pyrimido[1,2-a]pyrimidin-4-one hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 7,7-Dimethyl-2-(pyridin-4-yl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one | HCID 135738616 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Bromo-7,7-dimethyl-2-(pyridin-4-yl)-6,7,8,9-tetrahydro-4h-pyrimido[1,2-a]pyrimidin-4-one hydrobromide | HCID 136374458 | — |
Reaction Steps
To a solution of 3.0 g (11.7 mmol) of 7,7-dimethyl-2-(pyridin-4-yl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one in 75 ml of acetic acid was added dropwise 0.6 ml (11.7 mmol) of bromine. The mixture was allowed to stir at room temperature for 2 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07214682B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-f23ba01a33de4779b6655b19f7780ef8 |
| Source note | uspto-grants-2007_05 |