1,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2) → N-(3-Dimethylaminophenyl)-2-(3,5-dimethyl-1H-pyrrol-2-yl)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-acetamide

HRID 1350185Notes

Reaction equation

HRID 1350185 reaction equation
[CH3:1][C:2]1[CH:6]=[C:5]([CH3:7])[NH:4][C:3]=1[C:8](=[C:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[NH:14][C:13]1=[O:21])[C:9](O)=[O:10].Cl.Cl.[CH3:24][N:25]([CH3:33])[C:26]1[CH:27]=[C:28]([CH:30]=[CH:31][CH:32]=1)[NH2:29]>>[CH3:24][N:25]([CH3:33])[C:26]1[CH:27]=[C:28]([NH:29][C:9](=[O:10])[C:8]([C:3]2[NH:4][C:5]([CH3:7])=[CH:6][C:2]=2[CH3:1])=[C:12]2[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[NH:14][C:13]2=[O:21])[CH:30]=[CH:31][CH:32]=1

Participants

3

Reactant 2

HCID 771241,3-Benzenediamine, N1,N1-dimethyl-, hydrochloride (1:2)HCID 69453471HCID 69453471, compound

Product 1

HCID 69507353N-(3-Dimethylaminophenyl)-2-(3,5-dimethyl-1H-pyrrol-2-yl)-2-(2-oxo-1,2-dihydroindol-3-ylidene)-acetamideYield 25.1%

Procedure

(3,5-Dimethyl-1H-pyrrol-2-yl)-(2-oxo-1,2-dihydroindol-3-ylidene)-acetic acid (90 mg) was reacted with 3-dimethylaminoaniline dihydrochloride (85 mg) using method B to give 32 mg (25%) of the title compound.

Sources & evidence

ORD record
ord-2821f05ec24b4acf9f9d5cb622d7bbea
Source dataset
uspto-grants-2007_05
Patent number
US07214700B2

Reaction notes

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