Bis(2-Methoxyethyl)amine → HCID 60077678, compound

HRID 1350252Notes

Reaction equation

HRID 1350252 reaction equation
[CH:1]1([CH2:7][CH2:8][CH2:9][C@@H:10]([C:19]2[O:23][N:22]=[C:21]([CH2:24]OS(C3C=CC(C)=CC=3)(=O)=O)[N:20]=2)[CH2:11][C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:36][O:37][CH2:38][CH2:39][NH:40][CH2:41][CH2:42][O:43][CH3:44]>>[CH3:36][O:37][CH2:38][CH2:39][N:40]([CH2:24][C:21]1[N:20]=[C:19]([C@H:10]([CH2:9][CH2:8][CH2:7][CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[CH2:11][C:12]([O:14][C:15]([CH3:18])([CH3:16])[CH3:17])=[O:13])[O:23][N:22]=1)[CH2:41][CH2:42][O:43][CH3:44]

Participants

3

Reactant 2

HCID 2383Bis(2-Methoxyethyl)amineHCID 16747945tert-Butyl (3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)1,2,4-oxadiazol-5-yl]hexanoate

Product 1

HCID 60077678HCID 60077678, compound

Procedure

Method as for preparation 5 using tert-butyl(3R)-6-cyclohexyl-3-[3-({[(4-methylphenyl)sulfonyl]oxy}methyl)-1,2,4-oxadiazol-5-yl]hexanoate (preparation 177) (500 mg, 0.99 mmol) and bis-(2-methoxyethyl)amine (280 μl, 1.98 mmol) as starting materials.

Sources & evidence

ORD record
ord-2b9b2944303941deb724ba9c2684d5b7
Source dataset
uspto-grants-2007_05
Patent number
US07214694B2

Reaction notes

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