Ethylenediamine → HCID 21093446, compound

HRID 1350380Notes

Reaction equation

HRID 1350380 reaction equation
[CH2:1]([NH2:4])[CH2:2][NH2:3].C(N([CH2:10][CH3:11])CC)C.[C:12]1([CH3:24])[CH:17]=[C:16]([CH3:18])[CH:15]=[C:14]([CH3:19])[C:13]=1[S:20](Cl)(=[O:22])=[O:21]>>[CH3:24][C:12]1[CH:17]=[C:16]([CH3:18])[CH:15]=[C:14]([CH3:19])[C:13]=1[S:20]([NH:3][CH2:2][CH2:1][NH:4][S:20]([C:13]1[C:12]([CH3:24])=[CH:17][C:16]([CH3:18])=[CH:15][C:10]=1[CH3:11])(=[O:22])=[O:21])(=[O:22])=[O:21]

Participants

4

Reactant 3

HCID 3301EthylenediamineHCID 8471TriethylamineHCID 130462-Mesitylenesulfonyl chloride

Product 1

HCID 21093446HCID 21093446, compound

Procedure

By a method similar to Example 152, using ethylenediamine (0.9 g, 15 mmol), triethylamine (3.03 g, 30 mmol), 2-mesitylenesulfonyl chloride (6.56 g, 30 mmol) gives the title compound. Mass spectrum (electrospray): (m/z)=425.2 (M+1); 1H NMR (DMSO-d6): δ7.28 (br, 2H), 7.01 (s, 4H), 2.69–2.68 (m, 4H), 2.47 (s, 12H), 2.28 (s, 6H).

Sources & evidence

ORD record
ord-88598dd727c04072870de7ee6317a4ff
Source dataset
uspto-grants-2007_05
Patent number
US07214673B2

Reaction notes

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