Ammonium formate → HCID 58860672, compound

Participants

Reaction Steps

Dissolve (S)-1-benzyl-3-(2-naphthalen-1-yl-ethyl)-piperazine (1.07 g, 3.03 mmol) in ethanol (10 mL). Add ammonium formate (1.2 g, 19.0 mmol) and palladium hydroxide (200 mg, 20 wt. % on carbon) and heat to reflux. After 7 h, filter the palladium hydroxide and concentrate the filtrate. Combine with Example 422 and purify.

Provenance & Evidence