(S)-2-(2-Methoxy-benzyl)-piperazine → (S)-10-[3-(2-Methoxy-benzyl)-piperazin-1-yl]-2-methyl-4H-3-thia-1,4,9-triaza-benzo[f]azulene

Participants

Reaction Steps

By a similar method to the method of Example 460, using 2-methyl-4H-3-thia-1,4,9-triaza-benzo[f]azulen-10-ylamine(0.687 g, 2.98 mmol) and (S)-2-(2-methoxy-benzyl)-piperazine (0.615 g, 2.98 mmol) gives 0.437 g of the title compound as a yellow solid: mass spectrum (ion spray): m/z=420 (M+1); Analysis for C23H25N5OS(0.5 H2O): calcd: C, 64.46; H, 6.12; N, 16.34; found: C, 64.20; H, 5.77; N, 16.14.

Provenance & Evidence