Chlorotrimethylsilane → HCID 86602385, compound

HRID 1350543Notes

Reaction equation

HRID 1350543 reaction equation
[C:1](/[CH:3]=[CH:4]\[NH:5][C:6]([NH2:8])=[O:7])#[N:2].[CH3:9][Si:10]([CH3:13])([CH3:12])Cl.[Cl-].[Li+]>C[Si](C)(C)N[Si](C)(C)C>[CH3:9][Si:10]([CH3:13])([CH3:12])[N:8]([Si:10]([CH3:13])([CH3:12])[CH3:9])[C:6]([NH:5]/[CH:4]=[CH:3]\[C:1]#[N:2])=[O:7]

Participants

5

Reactant 3

HCID 6397ChlorotrimethylsilaneHCID 433294Lithium ChlorideHCID 14730407HCID 14730407, compound

Product 1

HCID 86602385HCID 86602385, compound

Reagents, catalysts & solvents 1

HCID 13838HexamethyldisilazaneSolvent

Procedure

83 g of cis-2-cyanovinyl urea was dissolved in 200 ml hexamethyldisilazane and 5 ml of trimethylchlorosilane and 1 g of lithium chloride were added. N2 was bubbled and the solution was refluxed until clear. Hexamethyldisilazane was then distilled off and N,N-bistrimethylsilyl-(cis-2-cyanovinylurea) was obtained, which was then dissolved in 200 ml anhydrous dichloromethane. To the solution, 1 g of CdCl2 was added and the solution was stirred with N2 bubbling.

Workup

  1. customN2 was bubbled
  2. temperaturethe solution was refluxed until clear
  3. distillationHexamethyldisilazane was then distilled off

Sources & evidence

ORD record
ord-e52823c017d8468b92cdb83f9287ca32
Source dataset
uspto-grants-2007_05
Patent number
US07214791B2

Reaction notes

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