HCID 178418361, compound → HCID 178445627, compound

Participants

Reaction Steps

The crude production of (E)-7-ethoxy-3-[2-[trans-4-(trans-4-butylcyclohexyl)cyclohexyl]ethenyl]-1,2,8-trifluoronaphthalene (16.6 g), 5% palladium-carbon (with 10% moisture) (3.1 g), tetrahydrofuran (100 ml) were added in an autoclave and reacted for 4 hours at room temperature under 4 atm of hydrogen. The reaction solution was filtrated with celite, and the filtrate was concentrated. Then, 7-ethoxy-3-[2-[trans-4-(trans-4-butylcyclohexyl)cyclohexyl]phenyl]-1,2,8-trifluoronaphthalene (9 g) was obtained.

Provenance & Evidence