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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1350665Generated: October 27, 2026

3-Azido-4-methylbenzoic acid → 3-[4-(5-Methoxy-pyridin-3-yl)-[1,2,3]triazol-1-yl]-4-methyl-benzoic acid

https://huagongshe.com/reaction/1350665

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Azido-4-methylbenzoic acidHCID 17973091—
Reactant3-[4-(6-Chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acidHCID 21097292—
Reactant3-Ethynyl-5-methoxypyridineHCID 21097349—
Product3-[4-(5-Methoxy-pyridin-3-yl)-[1,2,3]triazol-1-yl]-4-methyl-benzoic acidHCID 21097291—

Reaction Steps

3-[4-(5-Methoxy-pyridin-3-yl)-[1,2,3]triazol-1-yl]-4-methyl-benzoic acid was prepared from 3-azido-4-methyl benzoic acid and 5-ethynyl-3-methoxy pyridine in the same manner as 3-[4-(6-chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acid (Example 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07214802B2
Source datasetuspto-grants-2007_05
ORD IDord-1e6d443a37b14e1781d47081378e88d0
Source noteuspto-grants-2007_05