3-Azido-4-methylbenzoic acid → 3-Azido-N-(5-tert-butyl-3-cyano-2-methoxy-phenyl)-4-methyl-benzamide

HRID 1350782Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1350782
[N:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:7]([OH:9])=O)=[N+:2]=[N-:3].[NH2:14][C:15]1[C:16]([O:27][CH3:28])=[C:17]([CH:20]=[C:21]([C:23]([CH3:26])([CH3:25])[CH3:24])[CH:22]=1)[C:18]#[N:19].N(C1C=C(C=CC=1C)C(NC1C=C(C(C)(C)C)C=C(NS(C)(=O)=O)C=1OC)=O)=[N+]=[N-]>>[N:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[CH3:13])[C:7]([NH:14][C:15]1[CH:22]=[C:21]([C:23]([CH3:26])([CH3:24])[CH3:25])[CH:20]=[C:17]([C:18]#[N:19])[C:16]=1[O:27][CH3:28])=[O:9])=[N+:2]=[N-:3]

Komponenten

4

Edukt 3

HCID 179730913-Azido-4-methylbenzoic acidHCID 210792023-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamideHCID 210972973-Amino-5-(tert-butyl)-2-methoxybenzonitrile

Produkt 1

HCID 210973023-Azido-N-(5-tert-butyl-3-cyano-2-methoxy-phenyl)-4-methyl-benzamide

Versuchsvorschrift

3-Azido-N-(5-tert-butyl-3-cyano-2-methoxy-phenyl)-4-methyl-benzamide was prepared from 3-azido-4-methyl benzoic acid (U.S. Ser. No. 04/102,492) and 3-amino-5-tert-butyl-2-methoxy-benzonitrile in the same manner as 3-azido-N-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenyl)-4-methyl-benzamide (Example 15).

Quellen und Nachweise

ORD-Eintrag
ord-b8fa7c4a6ee24560ab3187e734d98d6a
Quelldatensatz
uspto-grants-2007_05
Patentnummer
US07214802B2

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