Trifluoroacetic acid → (4-tert-Butyl-3-fluorophenoxy)acetic acid

Participants

Reaction Steps

A mixture of tert-butyl (4-tert-butyl-3-fluorophenoxy)acetate (630 mg, 2.2 mmol), trifluoroacetic acid (3.0 ml), tetrahydrofuran (3.0 ml) and methylene dichloride (3.0 ml) was treated in the same procedure described in Example 3(c) to furnish 443 mg of the title compound which was used for further reaction without purification.

Provenance & Evidence