2-Morpholinoethylamine → HCID 21098023, compound

HRID 1351152Notes

Reaction equation

[CH2:1]([N:8]1[C:12]2=[N:13][C:14](S(C)(=O)=O)=[N:15][CH:16]=[C:11]2[C:10]([Br:21])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:22][CH2:23][CH2:24][N:25]1[CH2:30][CH2:29][O:28][CH2:27][CH2:26]1>>[CH2:1]([N:8]1[C:12]2=[N:13][C:14]([NH:22][CH2:23][CH2:24][N:25]3[CH2:30][CH2:29][O:28][CH2:27][CH2:26]3)=[N:15][CH:16]=[C:11]2[C:10]([Br:21])=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 4082852-Morpholinoethylamine

HCID 21098024HCID 21098024, compound

Product 1

HCID 21098023HCID 21098023, compound

Procedure

Prepared as described above in Example 8 starting from 1-benzyl-3-bromo-6-methanesulfonyl-1H-pyrazolo[3,4-d]pyrimidine and N-aminoethylmorpholine to give the title compound (1-benzyl-3-bromo-1H-pyrazolo[3,4-d]pyrimidin-6-yl)-(2-morpholin-4-yl-ethyl)-amine; LC/MS (m/e)=419.2 (MH+), Rt=1.47 min.

Workup

customPrepared

Sources & evidence

ORD record: ord-145d7eea50da41c7bc8012878f0a7731
Source dataset: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07217710B2

Reaction notes

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