Diisopropylethylamine → HCID 21098030, compound

Participants

Reaction Steps

2,3-Dichlorobenzenesulfonyl chloride (342 mg, 1.5 equiv.) was added to a mixture of 4-(6-Methanesulfonyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-phenyl amine (283 mg., 0.93 mmol) and DIEA (325 μl, 2 equiv.) in CH2Cl2 (10 ml) at room temperature. After 2 hrs, the mixture was diluted by CH2Cl2 (10 ml) and washed by 10% NaHCO3, brine, drying and concentration left 420 mg as a golden yellow solid; LC/MS(m/e)=512.0 (MH+).

Provenance & Evidence