HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)piperazine → 3-[4-(4-Fluorophenyl)-piperazine-1-sulfonyl]5,6-dihydro-4H-benzo[b]thiophene-7-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)piperazine | HCID 75260 | — |
| Reactant | 7-Oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonyl chloride | HCID 21098685 | — |
| Product | 3-[4-(4-Fluorophenyl)-piperazine-1-sulfonyl]5,6-dihydro-4H-benzo[b]thiophene-7-one | HCID 21098603 | — |
Reaction Steps
From 1-(4-fluorophenyl)-piperazine (91 mg) and 7-oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonyl chloride (the compound of Preparation Example 7) (120 mg), the title compound (148 mg) was obtained as a colorless solid, in the same way as Preparation Example 41.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217723B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-481339da71ad4265b6e5bef4df31bd50 |
| Source note | uspto-grants-2007_05 |