HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Amino-3-(4-chloro-phenoxy)-propan-2-ol → 7-Oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [3-(4-chloro-phenoxy)-2-hydroxy-propyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Amino-3-(4-chloro-phenoxy)-propan-2-ol | HCID 2770882 | — |
| Reactant | 7-Oxo-4,5,6,7-tetrahydrobenzo[b]thiophene-3-sulfonyl chloride | HCID 21098685 | — |
| Product | 7-Oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [3-(4-chloro-phenoxy)-2-hydroxy-propyl]-amide | HCID 21098682 | — |
Reaction Steps
From 1-amino-3-(4-chloro-phenoxy)-propane-2-ol (58 mg) and 7-oxo-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonyl chloride (the compound of Preparation Example 7) (70 mg), a yield (45 mg) was obtained as a colorless amorphous substance, in the same way as Preparation Example 41
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07217723B2 |
| Source dataset | uspto-grants-2007_05 |
| ORD ID | ord-a60e7abe57f44b1c9f5f20c053accb88 |
| Source note | uspto-grants-2007_05 |